Experimental Publications
2024
69. Cooperative intra- and intermolecular hydrogen bonding in scaffolded squaramide arrays. L. Martínez-Crespo, G. F. S. Whitehead, I. J. Vitórica-Yrezábal, S. J. Webb, Chem. Sci. 2024, Accepted Manuscript
68. Rapid, low-cost determination of Hg2+, Cu2+, and Fe3+ using a cellulose paper-based sensor and UV-vis method with silver nanoparticles synthesized with S. mammosum. F. Pilaquinga, J. Morey, P. Duel, G. S. Yáñez-Jácome, E. Chuisaca-Londa, K. Guzmán, J. Caiza, M. Tapia, A. Debut, K. Vizuete, M. N. Piña, Sens. Bio-Sens. Res. 2024, 45, 100680
67. Isothermal Phase Transitions in Liquid Crystals Driven by Dynamic Covalent Chemistry. D. Martínez, T. Schlossarek, F. Würthner, B. Soberats, Angew. Chem. Int. Ed. 2024, 63, e202403910
2023
66. Two-Dimensional Supramolecular Polymerization of a Bis-Urea Macrocycle into a Brick-Like Hydrogen-Bonded Network. L. Rubert, M. F. Islam, A. B. Greytak, R. Prakash, M. D. Smith, R. M. Gomila, A. Frontera, L. S. Shimizu, B. Soberats, Angew. Chem. Int. Ed. 2023, 62, e202312223
65. Chemically Fueled Communication Along a Scaffolded Nanoscale Array of Squaramides. L. Martínez-Crespo, I. J. Vitórica-Yreazábal, G. F. S. Whitehead, S. J. Webb, Angew. Chem. Int. Ed. 2023, 62, e202307841
64. Columnar liquid-crystalline J-aggregates based on N-core-substituted naphthalene diimides. E. Castellanos, R. M. Gomila, R. M. Veedu, G. Fernández, A. Frontera, B. Soberats, J. Mater. Chem. C 2023, 11, 10884-10892
63. Light-Driven Photoconversion of Squaramides with Implications in Anion Transport. M. Vega, L. Martínez-Crespo, M. Barceló-Oliver, C. Rotger, A. Costa, Org. Lett. 2023, 25, 3423-3428
62. Pathway-Controlled Aqueous Supramolecular Polymerization via Solvent-Dependent Chain Conformation Effects. L. Borsdorf, L. Herkert, N. Bäumer, L. Rubert, B. Soberats, P. A. Korevaar, Cole Bourque, C. Gatsogiannis, G. Fernández, J. Am. Chem. Soc. 2023, 145, 8882-8895
61. Bioinspired crowding directs supramolecular polymerisation. N. Bäumer, E. Castellanos, B. Soberats, G. Fernández, Nat. Commun. 2023, 14, 1084
60. Confinement effect of hydrolysis in small lipid vesicles. B. Woods, K. C. Thompson, N. Szita, S. Che , L. Milanesi, S. Tomás, Chem. Sci. 2023, 14, 2616-2623
59. High in vitro activity of gold and silver nanoparticles from Solanum mammosum L. against SARS-CoV-2 surrogate Phi6 and viral model PhiX174. F. Pilaquinga, R. Bosch, J. Morey, C. Bastidas-Caldes, M. Torres, F. Toscano, A. Debut, K. Pazmiño-Viteri, M. N. Piña, Nanotechnology 2023, 34, 175705
2022
58. One-Pot Environmentally Friendly Synthesis of Nanomaterials Based on Phytate-Coated Fe3O4 Nanoparticles for Efficient Removal of the Radioactive Metal Ions 90Sr, 90Y and (UO22+ from Water. P. Duel, M. N. Piña, J. Morey, Nanomaterials 2022, 12, 4383
57. Thermoreversible Polymorph Transitions in Supramolecular Polymers of Hydrogen-Bonded Squaramides. S. Bujosa, A. Doncel-Giménez, N. Bäumer, G. Fernández, E. Ortí, A. Costa, C. Rotger, J. Aragó, B. Soberats, Angew. Chem. Int. Ed. 2022, 61, e202213345
56. Synthesis and fluorescence of N-squaraine dianions derived from electron-deficient primary anilines. M. Vega, R. M. Gomila, J. Pons, A. Frontera, C. Rotger, A. Costa, Dyes Pigm. 2022, 207, 110746
2021
55. Silver nanoparticles as a potential treatment against SARS-CoV-2: A review. F. Pilaquinga, J. Morey, M. Torres, R. Seqqat, M. N. Piña, WIREs Nanomed. Nanobiotechnol. 2021, 13, e1707
54. Unveiling the Role of Hydrogen Bonds in Luminiscent N-Annulated Perylene Liquid Crystals. S. Bujosa, E. E. Greciano, M. A. Martínez, L. Sánchez, B. Soberats, Chem. Eur. J. 2021, 27, 14282-14286
53. CMOS-MEMS VOC sensors functionalizad via inkjet polymer deposition for high-sensivity acetone detection. R. Perelló-Roig, J. Verd, S. Roca, B. Soberats, A. Costa, J. Segura, Lab Chip 2021, 21, 3307-3315
52. Dual role of silver in a fluorogenic N-squaraine probe based on Ag(I)-π interactions. M. Vega, S. Blasco, E. García-España, B. Soberats, A. Frontera, C. Rotger, A. Costa, Dalton Transact. 2021, 50, 9367-9371
51. Raltitrexed-Modified Gold and Silver Nanoparticles for Targeted Cancer Therapy: Cytotoxicity Behaviour In Vitro on A549 and HCT-116 Human Cancer Cells. J. Morey, P. Llinás, A. Bueno-Costa, A. J. León, M. N. Piña, Materials 2021, 14, 534
50. Introducing a Squaramide-Based Self-Immolative Spacer for Controlled Drug Release. M. Ximenis, A. Sampedro, L. Martínez, G. Ramis, F. Orvay, A. Costa, C. Rotger, Chem. Commun. 2021, 57, 2736-2739
49. Influence of the Z/E Isomerism on the Pathway Complexity of a Squaramide-Based Macrocycle. F. Orvay, J. Cerdá, C. Rotger, E. Ortí, J. Aragó, A. Costa, B. Soberats, Small 2021, 17, 2006133
48. Effective Elimination and Biodegradation of Polycyclic Aromatic Hydrocarbons from Seawater through the Formation of Magnetic Microfibres. M. S. Gutiérrez, A. León, P. Duel, R. Bosch, M. N. Piña, J. Morey, Int. J. Mol. Sci. 2021, 22, 17
2020
47. Inducing Selectivity of Carbonaceous Material: Removing Noble Salts, Au3+, and Ag+ from Aqueous Media by Nanodiamonds Functionalized with Squaramides. M. S. Gutiérrez, K. A. López, J. Morey, M. N. Piña, Materials 2020, 13, 1086
46. Synthesis of Silver Nanoparticles Using Aqueous Leaf Extract of Mimosa albida (Mimosoideae): Characterization and Antioxidant Activity. F. Pilaquinga, D. Amaguaña, J. Morey, M. Moncada-Basuato, J. Pozo-Martínez, C. Olea-Azar, L. Fernández, P. Espinoza-Montero, E. Jara-Negrete, L. Meneses, F. López, A. Debut, M. N. Piña, Materials 2020, 13, 503
45. Development of Plasmonic Chitosan-Squarate Hydrogels via Bio-Inspired Nanoparticle Growth. E. Castellanos, B. Soberats, S. Bujosa, C. Rotger, R. de la Rica, A. Costa, Biomacromolecules 2020, 21, 966-973
44. Self-assembly in water of amphiphilic aryl-squaramides driven by dipolar π-π interactions. S. Bujosa, E. Castellanos, A. Frontera, C. Rotger, A. Costa, B. Soberats, Org. Biomol. Chem. 2020, 18, 888-894
2019
43. Influence of the aromatic surface on the capacity of the adsorption of VOCs by magnetite supported organic-inorganic hybrids. M. N. Piña, M. S. Gutiérrez, M. Penagos, P. Duel, A. León, J. Morey, D. Quiñonero, A. Frontera, RSC Adv. 2019, 9, 24184-24191
42. Surface Modification of Pseudoboehmite-Coated Aluminium Plates with Squaramic Acid Amphiphiles. C. López, B. Galmés, B. Soberats, A. Frontera, C. Rotger, A. Costa, ACS Omega 2019, 4, 14868-14872
41. Synthesis and biological evaluation of new long-chain squaramides and anti-chagasic agents in the BALB/c mouse model. R. Martín-Escolado, C. Marín, M. Vega, A. Martín-Montes, E. Medina-Carmona, C. López, C. Rotger, A. Costa, M. Sánchez-Moreno, Bioorg. Med. Chem. 2019, 27, 865-879
2018
40. The role of N-Methyl squaramides in a hydrogen bonding strategy to fold peptidomimetic compounds. L. Martínez, E. Escudero, A. Costa, C. Rotger, Chem. Eur. J. 2018, 24, 1-13
39. Removal of Au3+ and Ag+ from aqueous media with magnetic nanoparticles functionalized with squaramide derivatives. P. Duel, M. S. Gutiérrez, P. Rodríguez, A. León, K. A. López, J. Morey, M. N. Piña, RSC Adv. 2018, 8, 36123-36132
38. In Vitro Activity of Squaramides and Acyclic Polyamine Derivatives against Trophozoites and Cysts of Acanthamoeba castellanii. M. Rosales, M. Ximenis, A. Costa, C. Rotger, D. Romero, F. Olmo, E. Delgado, M. Clares, E. García-España, C. Marín, M. Sánchez, J. Biosci. Med. 2018, 6, 1-14
37. Water-Soluble Squaramide Dihydrates: N-Methylation Modulates the Occurrence of One- and Two-Dimensional Water Clusters through Hydrogen Bonding and Dipolar Interactions. M. Ximenis, J. Pitarch-Jarque, S. Blasco, C. Rotger, E. García-España, A. Costa, Cryst. Growth. Des. 2018, 18, 4420-4427
36. Adsorption and Quantification of Volatile Organic Compounds (VOCs) by using Hybrid Magnetic Nanoparticles. M. N. Piña, P. Rodríguez, M. S. Gutiérrez. D. Quiñonero, J. Morey, A. Frontera, Chem. Eur. J. 2018, 24, 12820-12826
35. A Very Highly Efficient Magnetic Nanomaterial for the Removal of PAHs from Aqueous Media. M. S. Gutiérrez, P. Duel, F. Hierro, J. Morey, M. N. Piña, Small 2018, 14, 1702573
2017
34. Binding Mode and Selectivity of a Scorpiand-Like Polyamine Ligand to a Single- and Double Stranded DNA and RNA: Metal- and pH-Driven Modulation. M. Inclán, L. Guijarro, I. Pont, J. C. Frías, C. Rotger, F. Orvay, A. Costa, E. García-España, M. T. Albelda, Chem. Eur. J. 2017, 23, 15966-15973
33. The Mouse in a Trap: Observation of a C(sp3)-F···F-C(sp3) Interaction in a Discrete CFC Pair by the Crystal Sponge Method. E. Sanna, A. Bauzá, E. C. Escudero-Adán, C. Rotger, A. Frontera, A. Costa, Cryst. Growth Des. 2017, 17, 3611-3615
32. Supramolecular Hydrogels Based on Minimalist Amphiphilic Squaramide-Squaramates for Controlled Release of Zwitterionic Biomolecules. C. López, M. Ximenis, F. Orvay, C. Rotger, A. Costa, Chem. Eur. J. 2017, 23, 7590-7594
31. Fast microwave-assisted conjugation of magnetic nanoparticles with carboxylates of biological interest. M. S. Gutiérrez, M. N. Piña, J. Morey, RSC Adv. 2017, 7, 19385-19390
30. Kinetic Analysis and Mechanism of the Hydrolytic Degradation of Squaramides and Squaramic Acids. M. Ximenis, E. Bustelo, A. G. Algarra, M. Vega, C. Rotger, M. G. Basallote, A. Costa, J. Org. Chem. 2017, 82, 2160-2170
2016
29. Effective anti-leishmanial activity of minimalist squaramide-based compounds. C. Marín, M. Ximenis, I. Ramírez-Macías, C. Rotger, K. Urbanova, F. Olmo, R. Martín-Escolano, M. J. Rosales, R. Cañas, R. Gutiérrez-Sánchez, A. Costa, M. Sánchez-Moreno, Exp. Parasitol. 2016, 170, 36-49
28. Macrocyclic Tetraimines: Synthesis and Reversible Uptake of Diethyl Phthalate by a Porous Macrocycle. E. Sanna, E. C. Escudero-Adán, C. López, P. Ballester, C. Rotger, A. Costa, J. Org. Chem. 2016, 81, 5173-5180
2015
27. Unexpected Squaramide-Induced Cleavage of Benzils: Synthesis and Characterization of Mono-Aroyl Squaramides. E. Sanna, C. López, P. Ballester, C. Rotger, A. Costa, Eur. J. Org. Chem. 2015, 7656-7660
26. A crystalline sponge based on dispersive forces suitable for X-ray structure determination of included molecular guests. E. Sanna, E. C. Escudero-Adán, A. Bauzá, P. Ballester, A. Frontera, C. Rotger, A. Costa. Chem. Sci. 2015, 6, 5466-5472
25. Hydrogen Bonded Squaramide-Based Foldable Module Induces Both β– and α-Turns in Hairpin Structures of α-Peptides in Water. L. Martínez, G. Martorell, A. Sampedro, P. Ballester, A. Costa, C. Rotger, Org. Lett. 2015, 17, 2980-2983
2014
24. Synthesis, X-ray characterization and DFT studies of bis-N.imidazolpyrimidine salts: the prominent role of hydrogen bonding and anion-π interactions. F. Orvay, A. Bauzá, M. Barceló-Oliver, A. García-Raso, J. J. Fiol, A. Costa, E. Molins, I. Mata, A. Frontera, CrystEngComm 2014, 16, 9043-9053
23. Cell Uptake and Localization Studies of Squaramide Based Fluorescent Probes. A. Sampedro, R. Villalonga-Planells, M. Vega, G. Ramis, S. Fernández de Mattos, P. Villalonga, A. Costa, C. Rotger, Bioconjugate Chem. 2014, 25, 1537-1546
22. Highly efficient coordination of Hg2+ and Pb2+ metals in water with squaramide-coated Fe3O4 nanoparticles. J. Morey, K. A. López, M. N. Piña, D. Quiñonero, P. Ballester, J. Mater. Chem. A. 2014, 2, 8796-8803
21. Antifolate-modified iron oxide nanoparticles for targeted cancer therapy: inclusion vs covalent union. K. A. López, M. N. Piña, R. Alemany, O. Vögler, F. Barceló, J. Morey, RSC Adv. 2014, 4, 19196-19204
20. Synthesis and Biological Evaluation of N, N’-Squaramides with High in Vivo Efficacy and Low Toxicity: Toward a Low-Cost Drug against Chagas Disease. F. Olmo, C. Rotger, I. Ramírez-Macías, L. Martínez, C. Marín, L. Carreras, K. Urbanova, M. Vega, G. Chaves-Lemaur, A. Sampedro, M. J. Rosales, M. Sánchez-Moreno, A. Costa, J. Med. Chem. 2014, 57, 987-999
19. Programmed Enzyme-Mimic Hydrolysis of a Choline Carbonate by a Metal-Free 2-Aminobenzimidazole-Based Cavitand. B. Soberats, E. Sanna, G. Martorell, C. Rotger, A. Costa, Org. Lett. 2014, 16, 840-843
2013
18. Critical solvent thermodynamic effect on molecular recognition: The case of the complex formation of carboxylates and ammonium-squaramido based receptors. M. N. Piña, K. A. López, A. Costa, J. Morey. Thermochim. Acta 2013, 569, 104-111
17. Efficient microwave-assisted preparation of squaric acid monoamides in water. C. López, M. Vega, E. Sanna, C. Rotger, A. Costa, RSC Adv. 2013, 3, 7249-7253
16. Squaramide-Coated Fe3O4 Nanoparticles and their selective complexation with Carboxylate Anions in Water. K. A. López, M. N. Piña, J. Morey, Sensors and Actuators B-Chemical 2013, 181, 267-273
15. Molecular Recognition of Zwitterions: Enhanced Binding and Selective Recognition of Miltefosine by Squaramide-Based Host. C. López, E. Sanna, L. Carreras, M. Vega, C. Rotger, A. Costa, Chem. Asian J. 2013, 8, 84-87
2012
14. Synthesis of unsymmetrical mono and bis-squaramides with (3-aminopropyl)triethoxysilane (APTES) or Dopamine moieties K. A. López, M. N. Piña, J. Morey, Synlett 2012, 23, 2830-2834
13. Cyclosquaramides as Kinase Inhibitors with Anticancer Activity. P. Villalonga, S. Fernández de Mattos, G. Ramis, A. Obrador-Hevia, A. Sampedro, C. Rotger, A. Costa, ChemMedChem. 2012, 7, 1472-1480
12. Janus-Like Squaramide-Based Hosts: Dual Mode of Binding and Conformational Transitions Driven by Ion-Pair Recognition. B. Soberats, L. Martínez, E. Sanna, A. Sampedro, C. Rotger, A. Costa, Chem. Eur. J. 2012, 18, 7533-7542
11. Synthesis and conformational studies of peptide-squaramide foldable modules: a new class of turn-mimetic compounds. L. Martínez, A. Sampedro, E. Sanna, A. Costa, C. Rotger, Org. Biomol. Chem. 2012, 10, 1914-1921
10. Grafted squaramide monoamine nanoparticles as simple systems for sulfate recognition in pure water. E. Delgado-Pinar, C. Rotger, A. Costa, M. N. Piña, H. R. Jiménez, J. Alarcón, E. García-España, Chem. Commun. 2012, 48, 2609-2611
9. Mechanism of Action of Cyclic Oliosquaramides on DPPC Phospholipid Monolayers. J. Giner-Casares, J. Keller, C. Rotger, A. Costa, G. Brezesinski, ChemPhysChem. 2012, 13, 453-458
2011
8. Synthetic Tripodal Squaramido-Based Receptors for the Complexation of Antineoplastic Folates in Water. D. Quiñonero, K. A. López, P. M. Deyà, M. N. Piña, J. Morey, J. Eur. Org. Chem. 2011, 31, 6187-6194
2010
7. Squaramide-Based Reagent for Selective Chromogenic Sensing of Cu(II) through a Zwitterion Radical. E. Sanna, L. Martínez, C. Rotger, S. Blasco, J. González, E. García-España, A. Costa, Org. Lett. 2010, 12, 3840-3843
2009
6. Conventional Tetrakis(triphenylphosphine)palladium-Copper(I) Iodide-Catalyzed Sonogashira Coupling of Free and BOC-Protected Propargylic Amines “On Water”. B. Soberats, L. Martínez, M. Vega, C. Rotger, A. Costa, Adv. Synth. Cat. 2009, 351, 1727-1731
2008
5. Selective sensing of competitive anions by non-selective hosts: The case of sulfate and phosphate in water. M. N. Piña, B. Soberats, C. Rotger, P. Ballester, P. M. Deyà, A. Costa, New J. Chem. 2008, 32, 1919-1923
2007
4. Evidence of anion-induced dimerization of a squaramide-based host in protic solvents. M. N. Piña, C. Rotger, B. Soberats, P. Ballester, P. M. Deyà, Chem. Commun. 2007, 0, 963-965
2006
3. Efficient Macrocyclation of Preorganized Palindromic Oligosquaramides. C. Rotger, M. N. Piña, M. Vega, P. Ballester, P. M. Deyà, A. Costa, Angew. Chem. Int. Ed. 2006, 45, 6844-6848
2. Rational Design, Synthesis, and Application of a New Receptor for the Molecular Recognition of Tricarboxylate Salts in Aqueous Media A. Frontera, J. Morey, A. Oliver, M. N. Piña, D. Quiñonero, A. Costa, P. Ballester, P. M. Deyà, E. Anslyn, J. Org. Chem. 2006, 71, 7185-7195
1. DABCO-Induced Self-Assembly of a Trisporphyrin Double-Decker Cage: Thermodynamic Characterization and Guest Recognition. P. Ballester, A. Costa, P. M. Deyà, A. Frontera, R. Gomila, A. Oliva, C. Hunter, J. Am. Chem. Soc. 2006, 128, 5560-5569